Dextran CLIO Magnetic Nanoparticles - Amine

General Information
Amine-functionalized Dextran coated crosslinked iron oxide nanoparticles (CLIO-NH2) have 1-3 superparamagnetic Fe3O4 iron oxide cores (8-10 nm in diameter) imbedded within the matrix of dextran sugar strands of 40 kDa or 70 kDa size. Dextran strands are crosslinked to prevent their disassociation, ensuring long-term biological stability. Dextran surface has been functionalized with Amine NH2 groups.
 
Features
Highly biocompatible, non-toxic
Long term stable under physiological conditions
40 kDa and 70 kDa dextran coats are available
Highly magnetic
Can be easily conjugated to NHS-activated ligands
 
Applications
In vitroand in vivomagnetic labels for cells and tissues
Magnetic cell separation
Probes for MRI
 
Specifications
Iron Oxide Core Diameter: 8 – 10 nm
Hydrodynamic Diameter: 60 – 80 nm
Polydispersity Index (PDI): < 0.25
Nanoparticle Charge: Between -3 and -0.3 mV
Magnetization:  5 – 30 emu/g (room temperature)
Shelf life: > 1 year (4°C storage)
Supplied as liquid suspension in water