Dextran CLIO Magnetic Nanoparticles - Biotin

General Information
Biotin functionalized Dextran coated crosslinked iron oxide nanoparticles (CLIO-BIOT) have 1-3 superparamagnetic Fe3O4 iron oxide cores (8-10 nm in diameter) imbedded within the matrix of dextran strands of 40 or 70 kDa in size. Dextran strands are crosslinked to prevent their disassociation, ensuring long-term stability. Biotin is covalently conjugated to the nanoparticle surface.
 
Features
Highly magnetic
Highly biocompatible, non-toxic
Long term stable under physiological conditions
40 kDa and 70 kDa dextran coats are available
Easy loading of biomolecules through Streptavidin-Biotin interaction
 
Applications
In vitroand in vivomagnetic labels for cells and tissues
Magnetic cell separation
Probes for MRI
 
Specifications
Iron Oxide Core Diameter: 8 – 10 nm
Hydrodynamic Diameter: 60 – 80 nm
Polydispersity Index (PDI): < 0.25
Magnetization:  5 – 30 emu/g (room temperature)
Shelf life: > 1 year (4°C storage)
Supplied as liquid suspension in water