We follow a well-established synthesis strategy of citrate coated gold nanoparticles that offers high degree of control over their diameter, yields a highly monodisperse population and shows very little batch-to-batch variation. Functional groups are introduced onto nanoparticle surface by using a bifunctional polyethylene glycol (PEG) linkers: one end includes a thiol that covalently binds nanoparticle surface, while the other end contains the functional moiety.
Gold nanoparticles are supplied at concentrations between 10 OD and 50 OD (as measure at the maximum absorbance peak) and are available at 0.4 mL, 1 mL and 3 mL volumes.
More detailed information on nanoparticle synthesis, functionalization and characterization can be found here.
Spherical Gold Nanoparticles
NanoVIVO™ Gold Nanoparticle Line
Fluorescently Labeled Spherical Gold Nanoparticles
Fluorescent molecules are loaded onto nanoparticle surface using PEG spacer. To avoid the dye from being quenched by the nanoparticle, longer PEG spacer of 5 kDa or 10 kDa needs to be used to maintain separation between the dye and nanoparticle surface.