Recombinant Human Interleukin-4 (IL4) (Active)

Shipping Cost Note

Each Recombinant Protein price includes shipping cost to Canada and import fees. Please ask for a discounted quote if ordering multiple Cusabio products.

Delivery Time Note

This product is usually imported from the manufacturer after order placement. Please expect longer delivery times of 7-14 days.

Catalog No.

CSB-MP011659HUd7

Product Name

Recombinant Human Interleukin-4 (IL4) (Active)

In Stock

Yes

Activity

Yes

Research Area

Immunology

Uniprot ID

P05112

Gene Names

IL4

Alternative Names

Interleukin-4; IL-4; B-cell stimulatory factor 1 (BSF-1); Binetrakin;Lymphocyte stimulatory factor 1; Pitrakinra

Organism

Homo sapiens (Human)

Source

Mammalian cell

Expressed Region

25-153aa

Protein Length

Full Length of Mature Protein

Tag Info

C-terminal 10xHis-tagged

Target Protein Sequence

HKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS

16.3 kDa

Purity

Greater than 90% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU/ug as determined by LAL method.

Form

Lyophilized powder

Buffer

Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4

Resonstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Relevances

Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses .

References

An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis. LaMarche N.M., Hegde S., Park M.D., Maier B.B., Troncoso L., Le Berichel J., Hamon P., Belabed M., Mattiuz R., Merad M. Nature 625:166-174 (2024)

Function